Rutin
(from Sophora japonica)

Main benefits:
Vessels. Inflammation. Skin. Circulation. Immunity.

Origin and Source:
Rutin is a bioactive flavonoid glycoside primarily derived from the flower buds of Sophora japonica (Japanese pagoda tree). Known for its powerful vascular and antioxidant benefits, Rutin has been used in Traditional Chinese Medicine for centuries to support blood vessel integrity, inflammation control, and immune resilience. At NØØT, we use a high-purity Rutin extract to support formulas focused on circulatory health, skin vitality, and cellular protection.

NØØT Classification:

Rutin is a Vascular Defense Phytogen — a plant-based compound included for its role in microcirculation, oxidative stress defense, collagen preservation, and immune modulation. It’s especially valuable in blends targeting pregnancy circulation, skin aging, inflammation, and hormonal stress adaptation.

Key Benefits and Science

Capillary Strength & Circulation

Supports the integrity of blood vessel walls and capillaries, especially in the legs, skin, and eyes.
Commonly used for varicose veins, heavy legs, swelling, and vascular fragility — especially during pregnancy or hormonal shifts.

Skin Health & Collagen Preservation

Works synergistically with Vitamin C to stabilize collagen, reduce oxidative breakdown, and support skin elasticity.
Helps protect against UV-induced aging and visible redness.

Immune Modulation & Inflammation

Rutin helps regulate the inflammatory response and histamine release, making it useful in seasonal sensitivities, autoimmune modulation, and skin reactivity.
Antioxidant action protects against oxidative DNA damage and free radical load.

Pregnancy & Vascular Load

Often recommended to support circulation and blood vessel tone during pregnancy, especially when experiencing swelling, spider veins, or inflammation.
Non-stimulatory and generally well-tolerated under professional guidance during prenatal care.

Longevity & Cell Integrity

Rutin’s ability to modulate inflammation and vascular health makes it increasingly relevant in anti-aging and cellular protection protocols.
Helps reduce oxidative stress markers linked to chronic inflammation and premature aging.

Why It’s Good for You

Rutin is vascular intelligence in phytochemical form. Whether you’re navigating hormonal transitions, pregnancy-related circulation issues, or simply looking to protect your skin, cells, and vessel walls, this flavonoid delivers quiet but powerful defense. It stabilizes your body where modern life wears it thin — in the bloodstream, in the skin, and in the inflammatory cascade.

Usage

Used in NØØT formulations targeting skin aging, immune modulation, prenatal support, and vascular health. Often paired with Vitamin C, Resveratrol, Phytomelatonin, and collagen-supporting compounds to build structure, strength, and antioxidant depth.

Why We Include It in NØØT Formulas

Commonly used for vascular integrity, collagen preservation, pregnancy-related swelling, and oxidative protection
Bioavailable flavonoid with applications in skin longevity, inflammation control, and immune regulation
Filler-free, cruelty-free, and third-party tested for purity, botanical identity, and flavonoid content
Included in blends for skin-glow defense, prenatal microcirculation, and stress resilience through vascular stability
Safe, non-stimulant, and well-tolerated in pregnancy-adjacent protocols under guidance

📚 Reference Example:

Guardamagna O et al. Flavonoids and cardiovascular health: clinical and preclinical evidence. Nutrients. 2018.
Boyanova M et al. Rutin as a prenatal supplement: impact on vascular tone and inflammation. J Matern Fetal Neonatal Med. 2020.
Formica JV, Regelson W. Review of the biology of quercetin and related bioflavonoids. Food Chem Toxicol. 1995.