Rhodiola Rosea Extract
(Rhodiola rosea)

Main benefits:
Burnout. Cortisol. Mood. Endurance. Brain fog. Mitochondria. Fatigue. Longevity.

Origin and Source:
Harvested from cold, high-altitude regions like Siberia and Scandinavia, Rhodiola rosea has been used for centuries in Tibetan, Russian, and Nordic medicine to improve stamina, mental focus, and survival under extreme conditions. At NØØT, we use a standardized extract rich in rosavin and salidroside — the bioactive compounds responsible for its unique anti-fatigue, adaptogenic, and neuroprotective effects.

 

NØØT Classification:

Rhodiola is a Classic Adaptogen — but it goes beyond basic stress support. We include it in NØØT formulations not only for cognitive performance and resilience, but for its deeper role in HPA axis modulation, immune regulation, mitochondrial support, and recovery from systemic depletion — including post-viral fatigue and autoimmune-triggered crashes.

Key Benefits and Science

Mental Clarity Under Pressure

• Shown to support focus, short-term memory, and decision-making under high-stress, high-performance conditions.
•  Frequently used in burnout, high-output work environments, and emotional overload states.

Fatigue & Post-Viral Recovery

• Clinical studies show Rhodiola is communly known to improve energy levels, exercise tolerance, and mood in people with chronic fatigue and post-infection syndromes — including Long COVID.
  
• Supports mitochondrial energy metabolism, making it ideal for low-motivation fatigue, immune burnout, and cellular reactivation.

Cortisol Regulation & Stress Resilience

• Regulates the HPA axis, known to support buffer cortisol spikes and normalize circadian rhythm.
• Often included in formulations targeting anxiety, adrenal depletion, and mood swings from chronic stress or trauma.

Immune Balance & Autoimmune Regulation

• Emerging evidence suggests Rhodiola support modulate immune response, especially in stress-triggered autoimmune flares.
• Supports immuno-neuro-endocrine balance, crucial in recovery from overactivation or systemic inflammation.

 

Why It’s Good for You

Rhodiola doesn’t just help you “handle stress” — it helps you recover from the way stress has shaped your system. If you’re tired but wired, mentally foggy, emotionally flat, or physically drained from illness, overwork, or immune imbalance, Rhodiola meets you at the intersection of resilience and repair. It helps you climb back.

 

Usage

Used in NØØT blends designed for stress recovery, fatigue repair, immune resilience, and mental performance under pressure. Often stacked with Magnesium, L-Theanine, and NAD+ activators for full-spectrum support — especially in formulations addressing burnout, perimenopause, or Long COVID recovery.

 

Why We Include It in NØØT Formulas

• Proven adaptogen for chronic stress, post-viral fatigue, emotional burnout, and cognitive recovery
  
• Included in blends for those experiencing mitochondrial crash, immune stress, or autoimmune flare cycles
  
• Filler-free, cruelty-free, and standardized for rosavin and salidroside balance
  
• Third-party tested for purity, potency, and adaptogenic integrity
  
• Supports both performance enhancement and deep system repair — physically and mentally

 

📚 Reference Example:

• Darbinyan V et al. Rhodiola rosea in stress-induced fatigue—a double blind cross-over study. Phytomedicine. 2000.

• Panossian A, Wikman G. Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress—protective activity. Pharmaceuticals. 2010.

• Komarova Y et al. Rhodiola rosea in patients with long COVID symptoms: A promising adaptogenic strategy. Integr Med (Encinitas). 2022.