Niacin
(Vitamin B3)

Main benefits:
Cholesterol. Energy. Detox. Skin. Brain.

Origin and Source:
Niacin — also known as Vitamin B3 — is a water-soluble B-vitamin essential for cellular energy production and DNA repair. It exists in two key forms: nicotinic acid and niacinamide. At NØØT, we use non-flushing, bioavailable forms of niacin to support metabolism, nervous system health, skin vitality, and hormonal detox — without triggering unwanted reactions.

NØØT Classification:

Niacin is a Biofunctional Nutrient Matrix — not a phytogen, nootropic, or adaptogen, but one of the most essential micronutrients in NØØT’s system. It fuels mitochondrial activity, supports methylation, and activates NAD+ pathways — critical for longevity, detoxification, and emotional balance.

Key Benefits and Science

Cellular Energy & NAD+ Activation

Niacin is a precursor to NAD+, the molecule that fuels mitochondrial energy, DNA repair, and longevity.
Commonly used in anti-aging, detox, and brain-health protocols to support energy at the cellular level.

Hormonal Balance & Methylation Support

Plays a key role in estrogen metabolism, liver detox pathways, and mood-related neurotransmitter synthesis.
Especially important for individuals experiencing hormonal shifts, burnout, or poor methylation function.

Detoxification & Cholesterol Metabolism

Shown in research to support lipid metabolism, liver enzyme function, and clearance of fat-soluble toxins.
Frequently used in detox and cardiovascular support protocols — especially in non-flushing forms.

Mood, Sleep & Nervous System Regulation

Niacin supports the synthesis of serotonin, dopamine, and melatonin — influencing emotional balance, stress response, and sleep quality.
Often used in burnout and anxiety formulations to restore neurochemical stability.

Skin & Circulation

Known for improving microcirculation, skin tone, and overall cell regeneration.
Used topically and internally for radiant skin and vascular resilience.

Why It’s Good for You

Niacin is the ignition switch for energy, detox, and emotional clarity. Whether you’re feeling sluggish, hormonally overloaded, mentally foggy, or burned out — this vitamin quietly activates your internal systems. It supports your ability to repair, reset, and re-energize from the inside out.

Usage

At NØØT, we use Niacin in both ways:
As a standalone supplement for those targeting NAD+ production, detox, or energy restoration
As a functional cofactor in blends for hormonal balance, brain clarity, metabolism, and longevity

We select gentle, non-flushing forms to avoid discomfort while still delivering biological impact.

Why We Include It in NØØT Formulas

Essential for energy production, hormonal detox, and emotional regulation
Supports those experiencing fatigue, mood swings, estrogen overload, poor methylation, or cellular stress
Cruelty-free, filler-free, and always tested for purity, dose accuracy, and bioavailability
Included in blends for stress recovery, skin glow, hormonal resilience, and NAD+ activation
Available as a standalone for targeted metabolic and anti-aging support

📚 Reference Example:

Knip M et al. Safety of high-dose nicotinamide: a review. Diabetologia. 2000.
Bogan KL, Brenner C. Nicotinic acid, nicotinamide, and nicotinamide riboside: molecular mechanisms and health outcomes. Annu Rev Nutr. 2008