Magnesium Bisglycinate

Main benefits:
Sleep. Stress. Hormones. Muscles. Calm.

Origin and Source:
Magnesium Bisglycinate is a chelated form of magnesium bound to the amino acid glycine. This form offers superior absorption and gut tolerance compared to many common magnesium supplements like magnesium oxide or citrate. At NØØT, we use fully reacted, buffered Magnesium Bisglycinate — the gold standard for nervous system recovery, sleep, and hormonal balance.

NØØT Classification:

Magnesium Bisglycinate is a Neuro-Mineral Matrix — not a Nootropic, Adaptogen, or Phytogen by category, but an essential inclusion in NØØT’s formulations for its widely recognized role in nervous system regulation, muscle relaxation, hormonal stability, and stress recovery.

Key Benefits and Science

Stress Resilience & Cortisol Regulation

Commonly used in protocols targeting nervous system overload and chronic stress recovery.
Shown in studies to support cortisol balance and promote resilience in high-demand conditions.

Muscle Relaxation & Restless Leg Support

Frequently included in blends addressing neuromuscular tension, restless leg syndrome, and post-workout recovery.
Recognized for its role in promoting muscle relaxation and glycine-driven calm.

Sleep & Nervous System Repair

Shown to support GABA signaling and parasympathetic nervous system activity, contributing to deeper, more restorative rest.
Commonly included in nighttime formulations to ease pre-sleep overstimulation.

PMS & Hormonal Stability

Widely used for menstrual-related mood fluctuations, cramps, and fluid retention.
Especially relevant in perimenopausal protocols for emotional steadiness and metabolic support.

Brain Function & Emotional Clarity

Research links magnesium deficiency to symptoms like brain fog, low focus, and mood dips.
Magnesium Bisglycinate supports neurotransmitter balance, including serotonin and dopamine pathways.

Why It’s Good for You

Magnesium Bisglycinate is one of the most important foundational tools for recharging a depleted system. Whether you're dealing with hormonal turbulence, burnout, cognitive fog, or nighttime restlessness, this highly absorbable mineral works deep in the background to restore calm, balance, and clarity.

Usage

At NØØT, Magnesium Bisglycinate is used in formulas for sleep, PMS, nervous system resilience, and stress recovery. It's paired with ingredients like L-Theanine, Rhodiola, Lemon Balm, and B6 for layered support across mood, sleep, and performance.

Why We Include It in NØØT Formulas

Selected for its bioavailability, tolerability, and impact on hormonal and neurological balance.
Commonly used in blends addressing restless legs, PMS, sleep disruption, and emotional burnout.
Cruelty-free, filler-free, and fully chelated for optimal absorption.
Third-party tested for purity, elemental consistency, and absence of contaminants.
Integrated into stacks designed to support calm focus, hormonal regulation, and recovery from daily depletion.

📚 Reference Example:

Nielsen FH. Magnesium, inflammation, and obesity in chronic disease. Nutr Rev. 2010.
Walker AF et al. Magnesium supplementation alleviates premenstrual symptoms of fluid retention. J Womens Health Gend Based Med. 2000.